As she recovers from a recent violent psychotic break, Janie (Hagan)is subjected each day to a bizarre holistic health and wellness regimen designed, and enforced, by her lifelong nanny and caretaker, Irma (Crampton). Janie begins to veer off the road to recovery when she develops an obsession with a young woman, Savannah (Lane), that Janie feels an inexplicable yet profound connection to. The obsession turns increasingly invasive, and wedges all three women into an ever-tightening, and terrifying struggle for control. Will Janie pull herself back from the precipice of insanity? Or will she go over head-first, taking anyone nearby down with her?

In 2004, the managers of the Meadow View Motel Gordon and Reece use room 6 to videotape the intimacy of the guests to sell porn movies. When the mysterious Mr. Smith checks in with a young woman, they witness the sadistic psychopath guest stabbing and killing his mate. The footage is a success and they decide to make other snuff movies with Smith. When Caleb, who is traveling from Chicago with his fiancée Jessica and his best friend Tanner, decides to rest in Meadow View, they have a nightmarish night and try to survive from the sick intention of the gang.